iS Clinical Brightening Serum
From
$87.00
iS Clinical Brightening Serum is a lightweight, high-performance treatment designed to target hyperpigmentation, dark spots, and uneven skin tone. Offered at Transcendence Skin, this advanced formula combines botanical brighteners and gentle exfoliants to help visibly improve radiance, clarity, and skin texture. Ideal for clients seeking a more even complexion without the harshness of traditional brightening agents, it works to reduce the appearance of discoloration while maintaining skin integrity. Fast-absorbing and non-irritating, it delivers noticeable results with consistent use and can be easily incorporated into a results-driven, age-defying skincare regimen.
Quantity
Who It’s For
Ideal for all skin types seeking a non-irritating, hydroquinone-free solution to brighten discoloration and promote a more even complexion. Especially recommended for those with sun damage, melasma, or stubborn pigmentation concerns looking for gentle yet effective results.
How It Works
iS Clinical Brightening Serum works through five different pathways to visibly reduce pigmentation. It combines pharmaceutical-grade botanical extracts like Norwegian kelp, alpha-arbutin, and mushroom-derived kojic acid with gentle exfoliating agents like glycolic, lactic, and salicylic acids.
These actives inhibit melanin production, accelerate cell turnover, and fade discoloration without drying or irritating the skin.
What’s Inside
• Ascophyllum Nodosum Extract (Norwegian Kelp) – Reduces melanin communication and promotes gentle exfoliation to fade dark spots
• Alpha-Arbutin (1.0%) – A potent, non-irritating lightening agent that blocks melanin production and evens skin tone
• Polyporus Umbellatus (Mushroom) Extract (1.0%) – Natural kojic acid source to brighten and protect against microbial skin stressors
• Saccharum Officinarum (2.0%) – Sugarcane-derived glycolic acid to support exfoliation and enhance skin texture
• Vaccinium Myrtillus (2.0%) – A lactic acid source that hydrates while removing dull, pigmented cells
• Salix Alba (Willow Bark) Extract (1.0%) – Salicylic acid precursor that refines pores and boosts cell renewal.
Ritual & Application
- Apply 3–4 drops of iS Clinical Brightening Serum to the palm of the hand.
- Using fingertips, dab and smooth evenly over cleansed face and neck, or target areas with pigmentation.
- Use morning or night.
- Slight tingling is normal due to active botanical exfoliants.
About Transcendence Skin
Transcendence Skin is a luxury clinical skincare practice and curated boutique based in Sherman Oaks, California. We specialize in advanced, results-driven treatments and offer a carefully selected collection of professional skincare products. Every formula we carry is personally vetted and thoughtfully integrated into our treatment protocols, supporting optimal skin health both in the clinic and at home.
Full Ingredient List
Water, Glycerin, Ascophyllum Nodosum Extract, Alpha-Arbutin, Polyporus Umbellatus Extract, Vaccinium Myrtillus Fruit/Leaf Extract, Saccharum Officinarum Extract, Salix Alba Bark Extract, and other clinically supported botanical actives.
Net Weight
- 30 mL e 1 fl. oz.
- 15 mL e 0.5 fl. oz.






